No. The SIM uses the following criteria for predetermined roles. Note that this is not official, just from my observations. And this is in order (ie it searches for 2 only with the pitchers left over after it finds 1, etc.):
1) The highest IP/162 pitchers (enough to obtain 900+ IP in the rotation) are assigned as starters. (Limit 6 here, obviously)
2) The pitcher with the highest # of saves = Closer A
3) The pitcher with the highest # of IP/162 = Long A
4) As far as I can still, the SIM uses a rather random method of assigning setups and mopups. Or, at least, they utilize a stat that's not immediately apparent in the Team Center.
When determining autorest, it utilizes the User Settings, but tends to put anyone assigned as a mopup to 50.