Wrapping the vaccination thing up:
1) Anti-vaccinations is hardly a Republican issue. Mike is right. It's an extreme of both sides. Some Repubs don't want it mandated, but do it anyway. Some Dems don't want it mandated, because they think it causes autism.
It doesn't show on this chart by Mississippi was #1 in percent of vaccinations at 99.7% of all kids.
2. Rand Paul isn't going to get sunk by this. He has issues of pandering all across the spectrum.
3. The percent of people that will alter their vote based on past vaccination statements of Christie, Bush, Clinton, etc is probably about 0.000000001% of the electorate.